Mindfulness bij IBD (MindIBD)

Introduction and rationale

Inflammatory bowel diseases (IBD), consisting of Crohn’s disease (CD) and ulcerative colitis (UC), are chronic inflammatory conditions of the gastrointestinal tract. Many IBD patients suffer from psychological distress, reduced sleep quality and fatigue. The main focus of current treatment is often keeping IBD patients in remission with use of medication and sometimes surgery. Evidence in the guidelines on treatment of psychological distress and fatigue is still relatively scarce. Several studies suggest that offering Mindfulness Based Cognitive Therapy (MBCT) to patients with IBD could result in reduced psychological distress and improved quality of life. By performing this research and offering patients with IBD MBCT, we hope that we can reduce psychological distress and improve quality of life and quality of sleep.


To investigate if offering MBCT to patients with IBD could result in reduced psychological distress and fatigue and improved quality of sleep and quality of life. In addition, we also investigate cost-effectiveness and feasibility of implementation.


Patients treated in the Radboudumc, Jeroen Bosch Hospital, Canisius Wilhelmina Hospital and Rijnstate Hospital can participate within the research. Participants will be randomized to one of the two groups; treatment as usual or treatment as usual with MBCT. At different time points (start of research and after 3, 6, 9 and 12 months) participants will be asked to complete a number of questionnaires, have a short interview by phone draw blood and collect a faeces sample.  Participants will also be asked to wear a headband during the night’s rest for 14 nightsat two measurement moments (start of research and after 3 months). The headband measures the quality of sleep. In addition, participants are asked to wear the Fitbit for the first three months to analyze the sleep indirectly. Participants randomized in the treatment as usual group will be invited to participate in MBCT at the end of the study. In total, about 136 people will participate in the study.

Time period

The research will take place from October 2020 until October 2024. The first MBCT groups will start in September 2021.

Research team

The research is performed by Milou ter Avest (Medical doctor and PhD-student), Annelieke van Velthoven (PhD-student), Marloes Huijbers (psychologist and post-doc researcher), Loes Nissen (gastroenterologist) and Anne Speckens (professor in psychiatry). Different external institutes are also involved such as: Jeroen Bosch Hospital, Rijnstate Hospital, Canisius Wilhelmina Hospital and Donders institute.

More information

For more information you can contact:
Annelieke van Velthoven (Annelieke.vanVelthoven@radboudumc.nl) or Milou ter Avest (Milou.terAvest@radboudumc.nl)

T: 024-36 15447


Lees hier een interview met Marloes Huijbers, projectleider van MindIBD, in de Chroniek, het magazine van Crohn & Colitis NL.


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